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Sleep disturbances
Not enough sleep
Too much sleep
Sleep apnea
Shift work (changing shifts, night shifts)
Alcohol
Heart diseases
Congestive heart failure (fluid in lungs)
Cardiomyopathy (dysfunction of the heart muscle)
Lung diseases
Asthma
Emphysema or chronic obstructive pulmonary disease (COPD)
Pneumonia
Nutritional disorders
Malnutrition (kwashiorkor, protein deficiency or marasmus, total calorie deficiency)
Obesity
Vitamin deficiency (thiamine, B12, B6, folate, vitamin C)
Electrolyte disturbances
Low potassium
Low magnesium
Low or high calcium
Low sodium
Endocrine disorders
Low blood sugar or high blood sugar (diabetes)
High or low thyroid
Low cortisol (
High cortisol (Cushing disease)
Gastrointestinal disorders
Gastroesophageal reflux disease (GERD)
Peptic ulcer disease (PUD)
Neurological disorders
Multiple sclerosis
Stroke
Lou Gehrig disease
Infectious causes
Any chronic disease
HIV/AIDS
Tuberculosis
Hepatitis
Mononucleosis
Chronic fatigue syndrome
Urinary tract infections
Connective tissue disorders
Arthritis (osteoarthritis and rheumatoid arthritis)
Lupus (SLE)
Fibromyalgia
Acromegaly
General disorders
Cancer
Anemia (blood loss or not making enough blood)
Gynecologic
Pregnancy
Menopause
Exercise disturbances
Lack of exercise
Too much exercise (worn out)
Excessive workload
Psychological
Depression (loss of interest, ambition)
Anxiety
Grief
Stress
Blood pressure medications work by different mechanisms to decrease blood pressure. The ultimate decrease in blood pressure also means a decrease in the amount of work the heart is doing, which can lead to a feeling of fatigue. Sometimes, the drug works not only on the heart, but also on the central nervous system.
Beta-blockers
Calcium channel blockers
Diuretics
ACE inhibitors
Heart medications work in different ways to regulate the heartbeat. Fatigue can be related to the effects the medication has on the heart or to the effects that spill over to other areas of the body.
Digoxin (Lanoxin)
Amiodarone (Cordarone, Pacerone)
Procainamide (Promine, Rhythmin)
Psychological medications used to help depression and anxiety work by increasing neurotransmitters in the brain that have a calming effect on the body, thus stimulating fatigue.
Antidepressants
Antipsychotics
Antianxiety medications (such as diazepam [Valium] or zolpidem [Ambien])
Narcotics: Many pain medications are opiate derived. Drowsiness can be caused by opiates.
Acetaminophen and codeine (Tylenol with Codeine)
Hydrocodone and acetaminophen (Vicodin)
Oxycodone and acetaminophen (Percocet)
Propoxyphene and acetaminophen (Darvocet)
Muscle relaxants work to decrease the contraction of muscles. This relaxation can lead to total body relaxation, which may cause you to feel fatigued.
Cyclobenzaprine (Flexeril)
Carisoprodol (Soma)
Orphenadrine (Norflex)